with a normal select element, as soon as it has focused, without actually opening the dropdown, if you start typing, then it will automatically jump to the next option that literally matches the keys you typed in within a short timeframe.
Problem shown on example page, https://select2.org/getting-started/basic-usage, if you tab to the first regular select element, and just type “ha”, then you will see it automatically select the “Hawaii” option. If you tab to the select2 version, typing doesn’t select anything. You have to open actually open the dropdown to type-select. This breaks natural functionality that select elements had prior to being stylized with select2, namely that it requires an additional layer of interaction before user is able to select an element.