Select2 disabled in databind c#

I have an issue with select2, so far it’s a very powerful part of my development. Here’s the issue, I have a few dropdowns, textboxes and a grid I’m using to build a point of sale system.

When I add an item to the grid, all the dropdowns loose the select2 effect, so they return to normal dropdowns. What could be the cause? I don’t know why this happens? Note that I’m using an Ajax update panel, could this be inteferring with select2?